Two years is a long time, so ... who knows? :)
For Europe, I'm kinda towing my wife around and showing her all the cool shit I like. She's nervous about traveling due to weird dietary constraints, but once she gets there, I know she's gonna love it.
So we are spending the majority of our time in the UK. London > Stonehenge > Devon > Bath > Cardiff > Liverpool > Isle of Man > Islay > Edinburgh > Fountains Abbey > York... that's sort of the "loop" we are looking at right now. Then, maybe grabbing a flight from Leeds to Budapest, spend a weekend with friends, and then fly back to London for several days before we head home again.
It's not that adventurous, but I think we need to set a reasonable pace and level of comfort for my wife. Once she has that experience, I expect she'll be more willing to travel beyond the English-speaking countries. :-)