It's the former. I have four weeks' annual leave accrued because I haven't had the chance to take time off properly throughout the year. I plan to spend it on the couch.

This BBC news story about using gene therapy to treat Hunter syndrome is very timely.

This has surely been inevitable ever since CRISPR was developed.

In principle, is it that bad a thing? If it prevents people being born with Huntington's or early onset dementia, it strikes me as a net positive.

An obvious issue is (in-)equity of access. Especially for scenarios of people selecting for intelligence or physical performance. But in that respect I'd be arguing for improving public health funding so more would-be parents can access it.

Big work thing - the thing that has been my main work thing all year - got endorsed by the second highest committee last week. Scheduled for University Council approval first week of December.

I have leftovers that still need tidying, including a performance planning meeting with the boss (ostensibly annual, but the first one in three years), but I'm starting to check out.

I have January off. I want to buy a Steam Machine but I doubt they'll be available that early in 2026. Suppose I'll read, write and garden, instead.