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comment by blackfox026
blackfox026  ·  3897 days ago  ·  link  ·    ·  parent  ·  post: Why Mentally Ill People Should Have Access to E-Cigarettes

One thing I never see mentioned in articles like these is the specific pharmacology of tobacco vs. just nicotine. Tobacco contains MAOI (monoamine oxidase inhibitor) compounds which reinforce the activity of dopamine. These are what make nicotine addictive, and they might play a role in the positive effects nicotine has on schizophrenics. I really wish there would be more studies on the effects of pure nicotine administration vs. tobacco use.





ooli  ·  3897 days ago  ·  link  ·  

Are you saying that MAOI is only found in tobacco, and is part of the addiction? Do you mean eCig are less addictive than cigarettes?

That would explain why I know so much people making the move back from eCig to normal after a few weeks.

humanodon  ·  3896 days ago  ·  link  ·  

From what i've seen, most that switch back after a few weeks do so because they don't buy a decent e-cig, just the cheapest ones sold at gas stations. Part of it seems to be the aesthetics of nicer e-cigs too-- it sounds silly, but for a lot of smokers, image is part of the appeal and honestly nice e-cigs don't look cool when you're using them. As AlderaanDuran (I think) pointed out, e-cigs can sometimes look like dildos.

insomniasexx  ·  3896 days ago  ·  link  ·  

    e-cigs can sometimes look like dildos.

LOL! I absolutely agree - although I usually call them lightsabers. I like my skinny one. I have an ego c twist battery and a mini protank ii now. All my friends seem to have the fatty protanks and these massive batteries that you grip in your hand.

humanodon  ·  3896 days ago  ·  link  ·  

I wanted to get a mini protank II, but I got the regular one instead, as it was in stock. I don't get what all the complaints were about in regard to the protank II; I don't find it airy at all. Although, on my twist, it does have a "probe" type vibe (har har!).

insomniasexx  ·  3895 days ago  ·  link  ·  

I don't find it too airy. I do know when my battery is about to die though because I get airy hits. But that's because the battery isn't giving enough juice and doesn't have anything to do with the protank itself.

Also, I got Thug Juice when I did my last order of Hawk Sauce and I'm in love. Plus I feel gangsta. :P I can't remember what your preferences for juice are but, if you like Hawk Sauce or semi-fruity, semi-menthol, flavors that don't have any super distinctive taste (ie: watermelon or orange which taste exactly as expected), I would strongly recommend Thug Juice.

humanodon  ·  3894 days ago  ·  link  ·  

I haven't tried either of those flavors from Mt. Baker, but I've been wondering about them. I've got pear, vanilla and cucumber mint juices from Mt. Baker at the moment. I can't tell if the cucumber mint tastes different this time around because I ordered a different volume and it needs to steep more, if there's been some kind of mistake in mixing it, or if the mint gets muted in my protank for some reason.

Next time around I might get a little bottle of each of those to try out.

suckpoppet  ·  3893 days ago  ·  link  ·  

You guys should try the aerotank (or at least the base, as it works with the PT2 + 3). It basically is an adjustable valve that allows you to regulate how airy your draw is. The real win, though, is that it completely seals the connection with the battery, so no juice can get down there, which, I find, is the source of almost all gurgling.

humanodon  ·  3893 days ago  ·  link  ·  

Very cool. I was wondering what the deal with the Aerotank is, so thanks for the recommendation. I just looked up the base and it's surprisingly cheap. I'll have to try this.

lolsociety  ·  3896 days ago  ·  link  ·  

I own a nice e-cig but the more aesthetically pleasing V2 cigs have actually been my favorite I've tried.

humanodon  ·  3896 days ago  ·  link  ·  

I haven't tried a V2, but I'm open minded. What do you like about it, over your other e-cig(s) (other than the aesthetics)?

lolsociety  ·  3811 days ago  ·  link  ·  

Sorry for the late reply. I love the flavors, and the convenience. Menthol and green tea menthol are great to me, and for a cartridge-based e-cig, it's relatively cheap.

blackfox026  ·  3896 days ago  ·  link  ·  

Absolutely. There hasn't been much research done yet in humans, but check these studies out:

Monoamine Oxidase Inhibition Dramatically Increases the Motivation to Self-Administer Nicotine in Rats

Contribution of monoamine oxidase (MAO) inhibition to tobacco and alcohol addiction