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So your final unit measurement is something like estimated # of vesicles per mL? How do you approach patient dosing?
Yes that is the unit. The dosing here is obviously sort of a guess, because there's no animal testing to fall back on. We've done some dose ranging in other disease models, so we're kind of going by that plus some extra for a fudge factor. I've done enough tox work that I have a lot of confidence in the safety, so I don't think overdosing is a problem beyond waste. The lung is one of the prime targets for this and similar therapies, so hopefully we'll see an effect. The bar is low, so any bit will help.