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comment by mk
mk  ·  3441 days ago  ·  link  ·    ·  parent  ·  post: Cancer cells can ‘infect’ normal neighbours

Yeah. b_b and I were the first to show that functional miRNA is transferred between cells in 2010. Other folk had previously shown that harvesting exosomes that contained miRNAs and then treating cells with them had the effect; but we devised an experiment that showed that a specific miRNA is transferred naively at such a level that it significantly inhibited translation of its targeted protein in neighboring cells.

Probably my best work to date. It made the cover of the top cancer journal.





b_b  ·  3440 days ago  ·  link  ·  

And Nature, in their infinite wisdom, rejected that paper without review on the grounds that it was uninteresting. Forward thinkers, my ass. Publishing shit five years too late, eh? I'm not mad about it though, can't you tell?

mk  ·  3440 days ago  ·  link  ·  

Well, it was Cancer Cell. It would be awesome if Nature rejected them too, but then covered it in their news blog. I am sure it has happened before.

steve  ·  3441 days ago  ·  link  ·  

hellz to the yah… We can all say "we knew him when"

b_b  ·  3440 days ago  ·  link  ·  

    "we knew him when"...

...he had a job?

If Congress has their way, we'll all be out on our ass sooner rather than later. Write your Congressperson, boys and girls :)

steve  ·  3440 days ago  ·  link  ·  

if there was a way to funnel the money spent on attack ads during campaign seasons into convincing people to write to their congressmen… or hell - divert those dollars directly into science…

I wrote last year - I should probably do it again this year. Thanks for the reminder.