She picks up the microphone at 1'06 and 2'22" of the same video without the commentary.
1"06" - can't hear anything
2'22" - she's singing "Go Johnny Go" - so I suspect Bill Burr has a pickle up his ass.
He had something he wanted to say about men being controlled by women, so he attached his message to the video - but notice, he doesn't have any audio of Yoko Ono - he makes his own imitation of Yoko.
His rant is cute, but it's not about John and Yoko.