a thoughtful web.
Good ideas and conversation. No ads, no tracking.   Login or Take a Tour!
comment by hyperflare
hyperflare  ·  3236 days ago  ·  link  ·    ·  parent  ·  post: New Procedure Allows Kidney Transplants From Any Donor

Jesus, Kleinbl00. I was just trying to make a point about

    f you gave me a kidney I'd spend the rest of my life hopped up on all sorts of immunosuppressants so that I could keep it alive, functional and in my body. That's a 1:1 replacement, blood type and all biomarkers matching perfectly, and the body still knows it ain't natural. There's a reason we autotransfuse over blood transfusion: even though blood is simple compared to a kidney, and even though it only lasts about three months, our own stuff is our own stuff and other people's stuff is THE INVADER.

It appears that that will change in the foreseeable future. If refreshing the antibodies makes the reaction less severe, we can come up with more ways to temper the immune system. It's not a monolithic rule that cannot be changed.

If this comes across as "goading", I'm sorry. That's not my intention at all. I like this discussion and I've learned a lot!





user-inactivated  ·  3236 days ago  ·  link  ·  

Just in advance -- please don't become friendly and interesting person number 12 to leave this website because of him.

kleinbl00  ·  3236 days ago  ·  link  ·  

Then stop acting like I'm a fucking moron, you're a fucking genius, and that every long, thought-out, based-on-personal-experience-and-firsthand-knowledge point I make is instantly nullified by something you looked up on the internet and didn't read.

I'm not enjoying this. I'm hating every fucking minute of it. If you want to learn something, don't start with "you're wrong because I don't understand this."

Go ahead. Look at that thread again.

Do you realize that probably 3/4ths of my involvement in Hubski for the past week has been patiently, and as inoffensively as I can, pointing out your misconceptions? Has been refusing to rise to the bait? Has been me, attempting to broaden your knowledge, despite the fact that you're only in it for the snark?

Know how you have this conversation?

"Hey, KB - you said that kidney transplants are going to spend the rest of their lives hopped up on immunosuppressants yet here's this article talking about universal kidney transplants! What gives?"

To which I would say

    For some reason — exactly why is not known — the person’s regenerated antibodies are less likely to attack the new organ, Dr. Segev said. But if the person’s regenerated natural antibodies are still a concern, the patient is treated with drugs that destroy any white blood cells that might make antibodies that would attack the new kidney.

That's NYTspeak for "hopped up on immunosuppressants."

For the foreseeable future.

Which, by the way, has a mortality rate of 25% after eight years.