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- There are also more than 7,000 cancers of the head and neck in the U.S. every year deemed "potentially HPV-associated," according to the CDC. Around 5,700 of those are in men. That's in addition to 3,000 HPV-associated anal cancers (1,100 in men), 2,300 new cases of vulvar cancer, 800 penile, and 600 vaginal. The vaccine could prevent many, though an unclear number, of these cases.