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comment by thundara
thundara  ·  3456 days ago  ·  link  ·    ·  parent  ·  post: Your brain is like a wad of paper

Tangentially related: do you know how brain folds are patterned to begin with? Is it marked by a molecule early in development or do they tend to grow / fold over time (i.e. during child / teen years)?





caeli  ·  3456 days ago  ·  link  ·  

This article seems promising. It looks like it's mostly about the mechanics and less about how genetics & development are involved though. Wish I could be more helpful but I'm not in this field...

thundara  ·  3456 days ago  ·  link  ·  

Mechanics is one way to explain it. I was imagining the folds developed as a result of some sections being initially more rigid than others, and the outer portions of the folds grew away from the rigid regions. But it also makes sense that there would be a pulling force of sorts to move / hold the inner sections closer to the center of the brain...