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Really my issue with your analysis is looking at bulk numbers instead of proportions of the population, which end up being roughly an order of magnitude difference between the proportion of trans population murdered in 2015 (smaller) compared to the proportion of opioid users killed via overdoes in 2015 (larger). Does bridge the gap quite a bit compared to the bulk but, if you're judging your reaction based on number/proportion of people killed, opioids still "win".