While my proteomics are a little less crazy than yours (only a surface biotinylation assay) I can relate.
I always have the feeling the proteomic methods (specially SDS-PAGE) are the least advanced compared to all the DNA/RNA stuff. Of course, this has a lot to do with the instability of proteins and handling but still, it is annoying.
Messed up a PCR? no problem, doing another one is fast.
Messed up a western? Oh, you don't have enough material left for another one? You had to sacrifice two mice to get enough material for one? The next batch of suitable mice is in 5 weeks? fuck this shit.
I was recently invited to try bouldering. Maybe I should try it out. Actually, my room has loft bed with bouldering stuff (no idea how they are called) attached to it. The guy who lived here before used to boulder/climb.