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No, I'm just saying that self-referential stuff has been around for 50 years and the world hasn't ended. Your example of "Ever since Ferris Bueller" is at least 20 years past patient zero, and that's only the patient zero I know of. John Gardner made much about the modern history of metafiction, but the practice dates back to the Canterbury Tales at least, and Gilgamesh at most. It's entirely possible that Deadpool is just a successful Howard the Duck.