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There are things we can't predict, because they're too complex. These problems will be solved in time. There are things we can't predict, because they're too chaotic, so effectively they're not determinate systems. These problems we can always estimate better with more information. Then there are things we can't predict, because the problems don't lend themselves, in principle, to the typical materialistic type evaluations. Language, for example, is a metaphysical phenomenon (I mean the language itself, not the way each of us produces it). Psychology exists somewhere on the boundary of language and biology, and is thus not entirely penetrable to biologic investigation.