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comment by mk
mk  ·  523 days ago  ·  link  ·    ·  parent  ·  post: Pubski: October 20, 2021

The other day my wife mentioned to me that the J&J shot used an adenovirus. I replied that it couldn't be true. One failure of early gene therapy is that the human body raises immunity to the adenovirus vector, and thus, subsequent therapies using adenovirus fail because the body raises a response against it. Also, many people have innate immunity to adenovirus due to prior infection.

But it is true. The J&J vaccine uses adenovirus. So people that got J&J either nerfed it because of prior immunity, or will nerf it and possibly all other adenovirus therapies in the future.

On a related note, my pal's brother who was terminal and on chemo had a heart attack and died a few hours after his second Pfizer vax. He is unvaccinated, and is understandably fearful after his brother's death. I had to concede to him that it is possible that his brother's heart attack was related. It does put stress on the body and his brother was in very bad shape. I did advise him to get vaccinated however. He is healthy and in his 50s, and I assured him that covid is the greater risk. Hopefully he does. Then two days ago another friend texted that his elderly mother was in the hospital for a mini-stroke. He mentioned that she had her Pfizer booster just two days prior, but not in suspected connection, only that it was a good thing since she was in the hospital.

I suspect that these multiple vaccination doses come with a risk for elderly and weakened individuals. It sucks, but nothing is simple. I've had two Moderna shots, and I'll get my booster. We are probably going to face a day when we have hard evidence of vaccination risks, and it is going to be fuel for the anti-vaccination fire.

Started to paint something for my daughter's room, but it is starting to look too creepy.

kleinbl00  ·  523 days ago  ·  link  ·  

Three pfizers down. 2nd one sucked. 3rd one was manageable. We can't claim that severity of response equates to effectiveness without acknowledging that the shot taxes the body.

Put Totoro under one of those trees and it will cease to be creepy.

user-inactivated  ·  523 days ago  ·  link  ·  

Wow TIL about adenovirus. Astra Zeneca also uses adenovirus, and was the most common vaccine here until recently!