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mk  ·  1490 days ago  ·  link  ·    ·  parent  ·  post: Pubski: March 25, 2020

    Furin activity exposes the binding and fusion domains, essential steps for the entry of the virus into the cell. Since the S- glycoprotein of all coronaviruses contains a similar furin cleavage site, it is plausible that the activity of this enzyme is essential for the zoonotic transmission of many coronaviruses, including Covid-19 enveloped by a MERS-CoV and Sars-CoV S glycoprotein containing a furin cleavage site.

    ...

    In these perspectives, likely, targeting furin might be an option for the prevention or treatment of Sars-CoV2 infection.

So yeah. Maybe inhibiting furin will work. The author theorizes it might help even more so in patients with heart issues.