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thundara  ·  2793 days ago  ·  link  ·    ·  parent  ·  post: Alzheimer's disease: Attack on amyloid-β protein

With regards to the blood-brain barrier, they only report that it does cross it. Other amyloid antibodies will bind amyloid precursor protein (which is cut to form the main component of amyloid plaques) on the surface of epithelial cells to help localize them to the brain. I can't find any discussion of the mechanism at play with this one though.