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I was discussing this with a friend and his thought was that if the government provided its own option to citizens, at a cost, it might be more acceptable.
I forget if it was discussed on here or somewhere else, but the reason the costs of pills are lower in other countries is that the single-payer gives the government a lot of leverage in bargaining with pharmaceutical companies to decide their prices. Medicare has a similar power, too a lesser extent, too, but the increased fragmentation of the insured population in the US lowers each's bargaining power.