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Very interesting article! And perhaps Lamarckian effects (methylation of transposons) can then alter the mutation rate, and thus 'natural selection'. Thus, Darwinian evolution could be guided by Lamarckian evolution. There's another mindfuck.This type of evolution has much subtler effects than selection for mutations, but it also works orders of magnitude faster. Maybe there was selective pressure on organisms to adapt quickly to changing environmental conditions. There's a mindfuck.