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Not much else to do but keep on living it, I guess. EDIT: I think this sounds flippant, but I do mean it. If she doesn't experience gender dysphoria and everyone around her considers her a woman, what else is there to do but keep going as before?
I suspect how difficult that is depends on how entrenched you are in gender-binary culture. On the other hand, those most entrenched in gender binarism are probably the same people who don't highly value science. Or, you could make fun of your husband for being gay? Start campaigning for half-gay marriage? Buy some snails and start referring to them as "my people."