by thundara

RNA interference (RNAi) was also used by JR Simplot of Boise, Idaho to silence PPO production in nonbrowning potatoes, which were approved by the USDA in November (Nat. Biotechnol. 33, 12–13, 2015). For that product, fragments of a single potato PPO gene were re-introduced into potato, activating the RNAi pathway. But unlike the apple, the potato's double-stranded RNA is formed by an inverted repeat transcribed in the tuber and processed into small interfering RNAs that ultimately silence their targets. JR Simplot's crop was also modified to have reduced acrylamide, which was achieved by using RNAi to silence the asparagine synthetase-1 gene (ASn1).