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BurnTheBarricade  ·  190 days ago  ·  link  ·    ·  parent  ·  post: Advanced breast cancer disappears after new immunotherapy

From what I can tell, this sort of falls into the 1st category, along with a bit of the 3rd. They take the patient's cells and look for a type of rare white blood cell called [tumor-infiltrating lymphocytes]( https://en.wikipedia.org/wiki/Tumor-infiltrating_lymphocytes) that can hit the cancer cells specifically, then make a bunch more of them and put them back into the patient. It's promising because the treatment is effectively an extension of the patient's own immune system (it won't provoke an immune response or poison the person's own cells), the TILs can reach anywhere that the bloodstream can reach (helping to deal with metastasis), and because there is potential for this type of therapy to work on multiple different types of cancers (rather than a specific drug targeting a specific cancer's oncogene).

I just finished The Emperor of All Maladies and it's a terrific read. The timing of this research result is pretty neat.

BurnTheBarricade  ·  191 days ago  ·  link  ·    ·  parent  ·  post: Advanced breast cancer disappears after new immunotherapy

22 months and counting. This may be the most promising case in the trial, so we still need to see what the other cases yielded, but that's still pretty good for a metastatic, resistant breast cancer. Does anyone see any potential downsides to the treatment besides cost? I'm thinking some sort of possible autoimmune response and the researchers' aforementioned concerns about the tumors evolving resistant proteins, but don't know precisely how big of a concern that is combined with the standard regimen.

Like francopoli said, preventative medicine should be able to generate revenue even with healthy people. Goldman Sachs sounds like their ideal business model would be to give everyone cancer and then jack up the price of chemo and immunotherapy. No such thing as a line they won't cross.

For some comedic relief, here's Mitchell and Webb predicting conversations like this in 2010.

BurnTheBarricade  ·  247 days ago  ·  link  ·    ·  parent  ·  post: FBI Raids Cohen’s Office

Suggested listening to accompany this article:

Johnny Cash - God's Gonna Cut You Down

user-inactivated  ·  249 days ago  ·  link  ·  

kleinbl00 probably has the real answer. I just like the name "Dead Cat Bounce."

kleinbl00  ·  249 days ago  ·  link  ·  

    Barely over 3 months into the year and already no fewer than 22 sessions with intra-day moves in the Dow of 400+ points. We had 1 all of last year. The only other time in the past have we seen so many 400 point moves bunched into such a short period -- Oct 2008 to Jan 2009.

- David Rosenberg

https://twitter.com/EconguyRosie/status/982293575286259712

BurnTheBarricade  ·  258 days ago  ·  link  ·    ·  parent  ·  post: Hubski Update: Change to our TOS

I contributed positively!!!!

Sorry, it doesn't happen that often. Love the site, y'all do good work.

BurnTheBarricade  ·  259 days ago  ·  link  ·    ·  parent  ·  post: Hubski Update: Change to our TOS

Also, when I hover over the little rectangle now, it still reads "Hubski 2017 Funding Goal." Not sure if you're the guy to talk to about that, or if it's an error on my end, but I figured mentioning it would be helpful.

mk  ·  259 days ago  ·  link  ·  

Oops. Thanks.

BurnTheBarricade  ·  258 days ago  ·  link  ·  

I contributed positively!!!!

Sorry, it doesn't happen that often. Love the site, y'all do good work.

BurnTheBarricade  ·  260 days ago  ·  link  ·    ·  parent  ·  post: The path forward on guns

True, I think otherwise there's potential for abuse in there to disenfranchise people even further.

BurnTheBarricade  ·  260 days ago  ·  link  ·    ·  parent  ·  post: The path forward on guns

I found this a couple of hours ago and was looking to see if anyone had posted it here! It almost perfectly encapsulates my thoughts on what actual progress might be possible. This is the solution, if we can get people to see it.

johnnyFive  ·  259 days ago  ·  link  ·  

Unfortunately that's a big "if" these days.

BurnTheBarricade  ·  265 days ago  ·  link  ·    ·  parent  ·  post: Hours After FOSTA Passes, Reddit Bans 'Escorts' and 'SugarDaddy' Communities

It's all part of a move to a sanitized social media platform. Which is a shame, since I tried for a long time to ignore the fact that it was turning into Facebook with strangers. Hopefully the niche subreddits will still keep their communities, which is really the only reason I go there now.

Quatermass  ·  265 days ago  ·  link  ·  

It absolutely is. Reddit was at its best when it was essentially a hub for random guru sites and insights into people's lives - the big subreddits, especially the defaults have been getting all the attention and advertising revenue, but the real gold has been down in the niche communities. And now it looks like they're moving to stomp out all that individuality and make the whole site into a series of ugly identikit pages serving up a bland paste that appeals to advertisers and investors.

And, coincidentally, here I am experimenting on Hubski all of a sudden, and I'm probably not the only person in this boat...

johnnyFive  ·  265 days ago  ·  link  ·  

Agreed. /r/neutralpolitics and some of the religion-oriented subs are about the only places I post anymore.

BurnTheBarricade  ·  265 days ago  ·  link  ·    ·  parent  ·  post: The Myth of Authenticity Is Killing Tex-Mex

    if the food is good, eat it

New t-shirt slogan right there.

BurnTheBarricade  ·  279 days ago  ·  link  ·    ·  parent  ·  post: Another Giant Step

The President has a track record of agreeing with whatever the last person to talk to him said. I don't really like where this is going.

kleinbl00  ·  279 days ago  ·  link  ·  

RAND has argued that the way forward on North Korea is amnesty for the intelligentsia and aristocracy so that the whole country can be reintegrated. Their model is German reunification which is to Korean unification what a shot glass is to a Big Gulp but hey, beats foxhole-to-foxhole trench warfare.

BurnTheBarricade  ·  279 days ago  ·  link  ·    ·  parent  ·  post: Pubski: March 7, 2018

Good luck! Looking forward to seeing your work and progress.

BurnTheBarricade  ·  285 days ago  ·  link  ·    ·  parent  ·  post: China using big data to detain people before crime is committed

I'll have to watch that sometime! It looks interesting. I was leaning more towards Minority Report but have only seen the last half of it.