OH man, building a D&D campaign is totally possible. It'd help if all the characters weren't Human though. You'd want to think about Elves, Dwarves, Halfings, etc - different innate skills - round out that par-tay! You could adapt it. Let's see our cast of characters.

thenewgreen is clearly a Bard with melee skills, race Human. Bards aren't typically great in combat though

mk our god is a Deus Ex Machina waiting for the heroes to get in over their heads (no character sheet, or NPC)

insomniasexx i'm going to say is half-elf, maybe a Ranger or (less likely IMO) Rogue

ButterflyEffect has gotta be some kind of magical artifact.

OftenBen is clearly a brawler, human or half-orc. he's gonna be your tank.

As for building a DnD campaign honestly really as DM you're mostly responsible for plot & setting. So unfortunately while we have these cool characters and archetypes it would be up to your players to pick and/or build them, though you could push your players certain ways in order to make a well-rounded team. For the D&D campaign it would not be hard since 8bit has done a lot of the work - you just steal his setting and the conflicts that arise. You already know, for instance, something about how Hubskina is laid out, so you don't have to make it up on your own.

The problem is that eventually storylines will diverge because they have to diverge and at that point you're making things up for yourself.

The work of running a campaign is about keeping the NPCs and the villains going accurately. At least that is my take on it. You have to build sheets for them, track their HP, whatever...that is where the legwork comes in as I perceive it.