My biggest issue with these functions is just trying to remember which set of functions goes with which label. (Hush does this this and this, Mute does this, etc.). If it were up to me, when I view each user's profile, rather than the labels, there'd be a series of checkboxes:

[ ] Hide this user's posts from feeds

[ ] Hide this user's comments

[ ] Don't allow this user to comment on my posts

[ ] Don't allow this user to send me notifications

[ ] Sort this user's comments to the bottom of threads

etc., and perhaps a catch-all:

[ ] ignore/hide this user entirely

Allows us more fine-grained controls and gets rid of the guessing game of what each function does.