Depends on the parents, a nice bottle of Champagne is great. Consider she's not been able to imbibe for some time. Conceivably, she can now. I know that with breastfeeding some women still won't touch it, but she can. Also depends on how much $ you want to spend. Gift certificate to their favorite restaurant with a promise to babysit? Spa for the mother. One really cool gift we got was from my cousin Samantha. She gave us a mixed CD of songs ideal for a baby/child that weren't "kids songs" but were soothing. Where the Sidewalk Ends? What are their interests? She plays guitar? Get the baby a mini-guitar. He's a writer? Monogrammed writing-paper with the baby's initials. Actually, baby's initials on anything is usually a big hit. Shows you put some time/thought in to it. Hope this was helpful.