Keep in mind: for all intents and purposes, once you hit 25 you've chosen every brand you'll ever choose. This is one reason why advertising focuses heavily on teenagers and young adults; it's easier to hack a presidential election than it is to get your mom to switch dish detergent. Macrobrews are kinda fucked in this regard because those goddamn whippersnappers tend to buy a sixer of something expensive and semi-local, but only every now and then: my roommate will buy six Blue Moons about three times a year while my dad will buy a half-rack of Coors Light once or twice a week. So they're marketing to a rarified stratum: people under 25 who are deciding on "their regular beer" that they can get most places. The Most Interesting Man came out in 2006 so everybody they could (legally) influence back then is between the ages of 35 and 40. Time to do something new because they know that even if they kill off The Most Interesting Man, you aren't going to switch to Corona at this late date. You started drinking Dos Equis to set yourself apart from those choads.
The owners of the macro brews give no fucks, of course. 70% of beer sales in the US are controlled by one fucking company.