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How about this then:there is likely a good reason that people who don't do those things are still alive, even if we don't know that reason yet. We need to be incredibly careful to fully understand the changes we are making when attempting to get rid of these diseases, and we are nowhere near the level of understanding required in order to safely make them yet, unless in the case where the person literally would die at birth, or be totally incapable of living a normal life.