I'll say this: once you've run a pi-hole it's really hard to go back. It's like "oh, this is what the designer wanted the website to look like before sales shoved a dozen banner ads in there" and also "sure am glad I'm not waiting six seconds for Akamai to load an Amazon product I'll never buy."
It fux with the on-demand services in... weird ways. I've blown enough holes in it for CBS to find their ad networks, but only just... which means the last six seconds of shows before commercial breaks are in silence, and the last six seconds of any ad package are also. And every now and then they mess with things so that, like, I can only partially browse CBS on my Playstation. But I'm more than willing to take that sacrifice.