This article is fucking tight. I love the random genetic sequences interspersed throughout it. Props to the authors and editors.
This accessory protein blocks signals that the infected cell would send out to the immune system. It also blocks some of the cell’s own virus-fighting proteins, the same ones targeted by other viruses such as polio and influenza.
Evolution is a crazy beast. Reminds me of the Feynman quote "nature's imagination is much greater than man's." Not in a good way in this case. My favourite class when I was still in high school was biochemistry. I rocked that shit and got almost 100 in the course but memorizing chemical names wasn't too hard. Uni-level biology is much harder as they have those multiple-multiple choice exams. We also got to play with a PCR machine, which was tight.
When new viruses try to escape a cell, the cell can snare them with proteins called tetherin. Some research suggests that ORF7a cuts down an infected cell’s supply of tetherin, allowing more of the viruses to escape. Researchers have also found that the protein can trigger infected cells to commit suicide — which contributes to the damage Covid-19 causes to the lungs.
I need to volunteer at a clinic when my symptoms subside. I have maximum respect for the healthcare workers on the front lines. I got tested today - I'm not going to know for 4 more business days. But still. These people are fucking badass. The lady that tested me came out of retirement to help out. I got the swab - it went so far up my nose I thought it was going to start bleeding.
I really need to go to grad school. Thanks for sharing.