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comment by mk
mk  ·  1462 days ago  ·  link  ·    ·  parent  ·  post: Pubski: March 25, 2020

    Furin activity exposes the binding and fusion domains, essential steps for the entry of the virus into the cell. Since the S- glycoprotein of all coronaviruses contains a similar furin cleavage site, it is plausible that the activity of this enzyme is essential for the zoonotic transmission of many coronaviruses, including Covid-19 enveloped by a MERS-CoV and Sars-CoV S glycoprotein containing a furin cleavage site.

    ...

    In these perspectives, likely, targeting furin might be an option for the prevention or treatment of Sars-CoV2 infection.

So yeah. Maybe inhibiting furin will work. The author theorizes it might help even more so in patients with heart issues.





kleinbl00  ·  1462 days ago  ·  link  ·  

I'm a believer. As a side benefit it's helping me sleep like a fucking log.

Now figure out what's in this magical panacea. It's the turbo-death pill my wife has been giving everyone when they get or start to get sick and it fucking works. The "I feel like shit" dose is 3 pills three times a day for three days and I tell you what I'm ready to try running again tomorrow and I'm on Day Two.

mk  ·  1462 days ago  ·  link  ·  

LOL it's like everything that everyone's grandmother told them to take when they are sick, but in one pill.

kleinbl00  ·  1462 days ago  ·  link  ·  

A pill that goes down sideways and gives you cayenne burps but fuckin' hell it's like Tamiflu for everything