Despite warnings by Jeremiah and others of the pro-Babylonian party, Zedekiah revolted against Babylon and entered into an alliance with Pharaoh Hophra. Nebuchadnezzar returned, defeated the Egyptians, and again besieged Jerusalem, resulting in the city's destruction in 587 BCE. Nebuchadnezzar destroyed the city wall and the Temple, together with the houses of the most important citizens. Zedekiah and his sons were captured, the sons were executed in front of Zedekiah, who was then blinded and taken to Babylon with many others. Judah became a Babylonian province, called Yehud, putting an end to the independent Kingdom of Judah. (Because of the missing years in the Jewish calendar, rabbinic sources place the date of the destruction of the First Temple at 3338 HC (423 BCE) or 3358 HC (403 BCE)).

This began the Babylonian Captivity of the Jewish (Hebrew) people.