I really enjoy Louis C.K.'s perspective, not just from a comedy standpoint, but I also think he has a great eye for universal truths that can be difficult to address but easy to relate to.
It's extremely difficult trying to explain this to people. Especially recently, when it seems that this is something I've wanted to do on a more regular basis. Whenever I try to explain, it results in weird looks and people thinking that I'm depressed or something's extremely wrong, even if they won't say it. Maybe they're right, maybe I am and maybe I should look into therapy, but maybe they're wrong, and maybe they just don't understand this kind of thinking. I think there's a lot of people out there that flat out have never thought of doing such a thing.
On a side note, I completely agree with insomniasexx. Louis is truly one of a kind.