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I don't think any of these light weight markup language are capable of eliminating the known edge cases without compromising their usability. You just have to find the right balance that fits your use case. The reason I lean towards (Multi)Markdown is because of the aforementioned wide adoption (lots of users know it; lots of solid libraries support it). Beyond those things it mostly just comes down to personal preference when selecting a markup language.'most cases' is what bites you in the ass with designing a markup. ;)